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Symbol
Name
ID
Gsk3b
glycogen synthase kinase 3 beta
MGI:1861437
Phenotype annotations related to nervous system
Darker colors indicate more annotations
Human Phenotypes
Dysphagia
Spasticity
Fatigable weakness of bulbar muscles
Fatigable weakness of swallowing muscles
Fatigable weakness of respiratory muscles
Motor neuron atrophy
Amyotrophic lateral sclerosis
Neurodegeneration
Fasciculations
Paralysis
Babinski sign
EEG abnormality
Dysarthria
Language impairment
Depression
Emotional lability
Delusion
Anxiety
Schizophrenia
Hallucinations
Atypical behavior
Negativism
Agitation
Cognitive impairment
Frontotemporal dementia
Social and occupational deterioration
Sleep abnormality
Hyperreflexia
Jaw hyperreflexia
Disease(s) Associated with GSK3B
amyotrophic lateral sclerosis
schizophrenia

Mouse Phenotypes
abnormal Wallerian degeneration
decreased prepulse inhibition
Availability Mouse Genotype
Gsk3btm2138.1Arte/Gsk3btm2138.1Arte
Gsk3btm1Jrw/Gsk3b+

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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Funding Information
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last database update
04/23/2024
MGI 6.23
The Jackson Laboratory